So the big tube that's still lighting up is likely the rectifier and that's because it's directly heated off a 5V winding from the power transformer. The rest of the tubes being cold says that the 6.3V filament supply is dead, and since they normally run the front panel light off the 6.3V filament supply, it being dead makes sense too.
Soo... either there's a fuse in the filament supply that is blown (I'd have to check a schematic to see if there is one) or the filament winding in the power transformer is toast, or the filament circuit has grounded out somewhere. The B+ circuit (high voltage) could easily still be running, so the inside of the amp is still crazy dangerous - but without filaments, tubes no workie.
I can crack it open and see what's going on with it if you want to drag it over here. I don't have the shop set up so may not be able to fix it, but ought to be able to tell you exactly what's wrong.