FWIW, I recently rode an ADV bike that had a 19" front wheel. On the street, I thought it was pretty awful compared to the 17" wheels on my Multistrada. Unless you're planning to spend significant amounts of time in the dirt, I'd stay away from bikes with 19" wheels...
Sorry but apples and oranges comparison... the wheel is much less important than the geometry, tires, weight distribution, suspension, etc. I have a Multi too but I don't think the 17" is a big factor in how it handles compared to say the 1190 Adv.
